A member asked:

How does lyrica (pregabalin) help with pain relief ?

A doctor has provided 1 answer
Dr. Paul Grin answered

Specializes in Pain Management

Main mechanism: It is believed to increase the rate of GABA synthesis in the brain. However, its main mechanism of action appears to be antagonism of NMDA receptors and calcium channel blockade.

Answered 2/12/2015

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