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A member asked:
How do tcas actually work to control non-migraine headaches? ssris aren't common for this, so is it the norepinephrine that is the agent helping?
A doctor has provided 1 answer
Great question: Great question! Norepinephrine is definitely involved in the interpretation of pain signals in various areas of the brain. However, serotonin definitely has a role to play (eg, the triptan drugs for migraine work on a specific subtype of serotonin). So, in theory, it's thought that these components together synergistically act to alleviate headache. Hope that helps!
Answered 1/30/2015
3.3k views
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