I am a 43 year old female, medicated for hypothyroid. i wake up after 4-5 hours sleep sweating and then have a lot of trouble going back to sleep. ?

Check thyroid level: You should have your thyroid level checked first to make sure you are not hyperthyroid on the medications. There are other conditions that can cause insomnia such as anxiety but these usually do not cause sweating which usually results from your body's thermoregulation. Make sure that you do not have a fever and if symptoms persist have your vitals checked and a comprehensive blood test.

Sleep study?: If your thyroid hormone levels are normal (on or off thyroid medication), then the most likely cause of your night sweats is obstructive sleep apnea.