Which enzymes help people to lose weight?

Orally? All digested: Biologic enzymes are primarily complex proteins, a tiny percentage of which utilize a particular vitamin (molecules present in the vast majority of foods) as a cofactor. All ingested proteins, including enzymatic proteins, are digested; i.e. broken down (to protect body from outside signals) to their amino acid building blocks & the amino acids are absorbed & used according to brain/body controls.