Monitor symptoms: A single double dose of hydrocodone/acetaminophen should not be too much of a problem. The main issue is with sedation, constipation (from hydrocodone), liver toxicity (from acetaminophen). Especially if you are also taking other medications. The maximum dose of acetaminophen/ day is 4 gram total from all sources (remember multi-symptom pain relievers may also have acetaminophen).
Answered 1/26/2015
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