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A 27-year-old member asked:

Nexium (esomeprazole) is not working what next?

2 doctor answers8 doctors weighed in
Dr. Michael Shim
Gastroenterology 21 years experience
Try something else: Get investigated for whatever symptom you're having to make sure you actually have reflux. If you do or already had investigation, may simply need a different med in that class.
Dr. Arthur Heller
Gastroenterology 44 years experience
Maybe not acid: Nexium (esomeprazole) is a ppi, potent minimizer of acid production in the stomach. Several other ppis on market-all roughly equivalent, can take days some respond better to one than another. Make sure the problem is truly acid related, or not. Other issues including gall bladder, pancreas, celiac sprue, cardiac can cause similar symptoms. Don't know your history, meds, risk factors, etc. Follow up with doc.
Last updated Jun 25, 2019

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