A member asked:

What causes a enlarged spleen?

5 doctors weighed in across 2 answers

Many causes : The spleen's job is to take older or damaged blood cells out of circulation. Diseases that cause abnormal or disrupted cells, like thallesemias and hemolytic anemia cause enlargement to compensate for the increased work. Congestion due to cirrhosis/portal hypertension cause enlargement by limiting blood flow out of the spleen. Tumors especially lymphoma can grow in the spleen as well.

Answered 12/22/2017

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Dr. Alan Ali answered

Specializes in Psychiatry

Enlarged spleen: Infectious mononucleosis, anemias, tumors, liver diseases.

Answered 8/27/2017

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