A member asked:

If you take a cyp450 3a4 inhibitor with a cyp4503a4 inducer, what happens?

A doctor has provided 1 answer

Complex question!: D, there exists a situation where a single drug acts as both inducer and affected drug, called autoinduction. Carbamazepine and artemisinin are examples of cyp3a4 and cyp2b6 substrates and inducers, respectively, that are known to exhibit autoinduction. Autoinduction is a phenomenon that can occur anytime a drug induces an enzyme which is also predominately involved in its own metabolic clea.

Answered 6/24/2014

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