Not long: Clindamycin has a relatively short half life and has to be dosed multiple times daily. But its most worrisome potential adverse effect, c. Difficile colitis, can persist long after the Clindamycin is gone. Take probiotics (at least yogurt) while on this med and if you develop signififcant diarrhea or cramps, get checked out.
Answered 7/10/2020
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