A member asked:

How long does clindamycin given during surgery stay in the system i had a reaction to it blistered rash and want to know how to minimize the reaction benedryl does not help ?

6 doctors weighed in across 2 answers

8 to 12 hours: Clindamycin is a drug which is given 3 c per day due to its short half life. It only stay in body for less than 12 hours.

Answered 6/24/2014

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Dr. Scott Grover answered

Specializes in Surgery

Only hours: Clindamycin is only around for a few hours. It should be completely gone by 24 to 36 hours. Reactions are commonly caused by histamine. Any antihistamine such as tagamet or Zantac (ranitidine) may provide some relief as well. You should make sure your doctor knows about your issues in case you need something stronger like steroids.

Answered 1/30/2019

5.6k views

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