A member asked:

Is it safe to take benadryl (diphenhydramine) after 3 glasses of wine if i feel i may have been exposed to a food allergy of mine?

2 doctors weighed in across 2 answers

Drowsiness: The risk you run is drowsiness from the benadryl (diphenhydramine). But if you are truly allergic to a food that you have eaten, then having an allergic reaction is much worse, even life-threatening. It takes awhile for Benadryl (diphenhydramine) to work, and you can become sick from food allergy very quickly. I would go to the er and sit in the waiting room. You don't have to check in, but in case you worsen, you are right there.

Answered 10/1/2017

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Dr. Alessandra Bertolucci answered

Specializes in Ophthalmology

NO: Benadryl (diphenhydramine) makes you groggy like a glass of wine. 3 glasses of wine makes most of the people very groggy. I don't know about you (depend of body mass and tolerance). Having an allergic reaction should be addressed as well especially after that drinking. If the allergic reaction is not severe you consider drinking as much water. If the reaction is severe you need to see a doctor.

Answered 5/1/2018

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