Suffer from rectal ulcer with sessile polyp, i have continuos bloody mucous bleeding with constipation, am on pentasa (mesalamine) what to do else?

Rectal Ulcer: You are on Mesalamine for uc? Of course, the bleeding and mucus is likely associated with active ulcerative colitis. A large sessile polyp, if it is a true polyp and not a uc pseudo polyp, can secrete mucus itself. It sounds to me that your ulcerative colitis is still not under control. Having said that, the rectal ulcer is likely associated also with your active disease. Get a 2nd opinion.