A member asked:
Is stiffness of arms and legs (appeared on 200mg of vitamin b6 a day taken for 3 mths) a symptom of sth serious or will it disappear with time?
4 doctors weighed in across 2 answers
Depends: B6 has two forms, active and inactive. Pyridoxal 5 phosphate p5p is the active form. Inactive b6 competes with p5p at the receptor. Some people do not convert b6 to p5p very well, so by taking high doses of inactive b6 can actually cause a functional deficiency due to receptor competition. Always take active b6.
Answered 11/11/2020
5.2k views
Prob. not related: It is unlikely to have toxicity from 200 mg of vitamin b6. If it is, it will almost always disappear if you stop it. If you do not start to improve, see your doctor because stiffness is not the usual symptoms from high b6.
Answered 1/21/2013
5.4k views
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