Maybe: If you treat with levothyroxine, lowering the tsh, the goiter may shrink. But often it does not, at least not much. There is also a risk of inducing hyperthyroidism. If there is a cyst, aspiration of the cyst may shrink the gland, but the fluid in the cyst often comes back. If the goiter is big and compressing airway or esophagus, surgery may be needed.
Answered 1/30/2019
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