HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

I'm symptomatic, ana & anti-dsdna neg. w/ a strong family history of sle. is it worth doing further testing like anti-sm (neg. for infection and iem)?

A doctor has provided 1 answer

What symptoms: No tests needed, clear history, objective evaluation! do not make yourself sick because of family history. The familial connective tissue diseases usualy have positive antibodies.

Dr Moeser and another doctor agreed

Answered 7/4/2015

5.3k views

Thank

Related Questions

A member asked:

Ana + 1:160 speckled anti native dsdna + 25.70iu/ml symptoms: hair thinning - do I have sle? Is hair thinning reversible w/ sle? Help very distressed

A doctor has provided 1 answer

A member asked:

I was +ve for ANA 1.48 & anti dsdna 28.5.Dr said its sle. Startd med in may, now went to diff dr n hospital & both tests came -ve.Is it due to med?

3 doctors weighed in across 2 answers

A member asked:

12 m ago ANA+1:160 and anti dsDNA+ 13 mLH. Treated for SLE in FL. I moved to PA. New Rheum re-tested and both negative. States it was never SLE . Is this normal for SLE or something else? Confsued

4 doctors weighed in across 2 answers

A member asked:

Sle diagnosed based on symptoms & below lab results. Ana 1.48 +ve, anti dsdna 28.5 +ve, ref <20, is there any chance these can be false positive?

A doctor has provided 1 answer

A member asked:

Should one seek appointment with rheumatologist if ANA positive occurs with several symptoms of sle only if dsdna comes back positive? (low WBC too)

2 doctors weighed in across 2 answers

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more

People also searched for:

I tested positive ANA and anti dsdna, later testing neg. I have past diagnosis that may apply to lupus but do not do well articuliatng at dr. Help?
ana 1280. Dsdna 23 iu/ml (<40 is neg), other ENA neg. Not yet tested for histone. Have some symptoms. Is dsdna significant here? Developing sle?
Negative ANA blood test but positive anti-dsDNA antibodies. Do I have lupus? What causes this? Very symptomatic.
ANA 1:160 homogenous, anti ssDNA 42, normal Rh factor, ESR, anti dsDNA , neg HLA B27. Tests due to severe joint pain- is this indicative of lupus??
Recur s/s worse recently fatigue joint pain/ rash- face and top of hands,raynauds/chilblains labs pos ANA titer pattern homogeneous. SOB/pain left rib protein in UA. EGFR 82. ST prednisone taper 120mg s/s better. dsdna- 25 iu/ml (neg?) Not lupus?

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.