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A 31-year-old female asked:

How long does ketamine stay in your system?

2 doctor answers3 doctors weighed in
Dr. Mark Gujer md fasa
Anesthesiology 27 years experience
Worried: Why are there so many questions like this on health tap? This is a controlled anesthesia drug! very dangerous in untrained hands. Sedation in normal doses last 1-2 hours. In your system much longer.
Dr. Tarek Shahbandar
Anesthesiology 23 years experience
I agree fully with above sentiment and concern. Ketamine is being used in some custom compounding creams on an outpatient basis though.
Mar 3, 2013
Dr. Norman Cohen
Anesthesiology 37 years experience
Depends on dose: Ketamine's drug level drops by 1/2 about every 2-2 1/2 hours. This is known as the half-life of the drug. At about 5 half-lives, the effect of a drug is usually considered insignificant. So at about 10-12 hours, the effects of ketamine from a typical dose is probably minimal. To some extent though, this is dose dependent. Large doses take longer to clear, small quicker.

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Last updated Feb 13, 2019
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