My son is 4 months and recently diagnosed with lissencephaly. he just started keppra (levetiracetam) 100 mg 2 weeks ago, but his seizures are more frequent now....

Infantile spasms: These sound like infantile spasms which 80% of children with lissencephaly have. After a few months, these kids often develop mixed seizure disorders including persisting infantile spasms, focal motor & generalized tonic seizures complex partial seizures, atypical absences, & atonic & myoclonic seizures. They can be difficult to control, but should be managed by a pediatric neurologist