Can optic nerve head drusen cause sudden unilateral loss of peripheral vision due to a spontaneous vascular event?

No: Optic nerve head drusen do not cause vascular events. Loss of vision due a vascular event is a serious problem that may be a warning sign for a life-threatening problem. See an ophthalmologist asap.

Disc Drusen: I am not aware of any association between optic nerve drusen and sudden unilateral vision loss from a vascular event. A vascular event should be evaluated and treated the same as if the disc drusen were not there.