For psoriasis,: Mutations in any of ~ 14 known genes confer susceptibility, with symptoms triggered by environmental factors, like streptococcal infections & stress. If you'e the only affected family member, your son's estimated risk is ~8-23%. If you're the only one with uc, his risk is ~ 15 x higher than the general population's. Genetic mutations in many different areas have been found in uc.
Answered 12/10/2013
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