A member asked:

What is deplin? would this work better than 5htp for anxiety and digestive issues?

A doctor has provided 1 answer
Dr. Pamela Pappas answered

Specializes in Psychiatry

Not by itself: Deplin is l-methylfolate (folic acid) -- the active form of folate (folic acid) (methyltetrahydrofolate (folic acid), or mthf). This form can cross the blood-brain barrier, without having to be metabolized from the folate (folic acid) in your multivitamin or in food. It can be used to augment antidepressant effect, and in this way can help treatment-resistant depression. This can help depressed people who have mthf deficiencies.

Answered 12/10/2013

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Are 5htp and GABA supplements effective for depression/anxiety?

4 doctors weighed in across 2 answers