A member asked:

Among the following , which is smallest . muscle fiber, thick filament , or myofibril ? which is largest ?

3 doctors weighed in across 3 answers
Dr. Jeffrey Satinover answered

Specializes in Psychiatry

Fiber>Fibril>Fila: Bundles of protein filaments create a myofibril, and many myofibrils comprise the contracting bundles within a muscle fiber, which is an elongated, contractile, cell. In the picture nearby, the smallest unit shown is a muscle fiber, i.e. One cell --exagerrated in crossesectional size, of course. So the myofibrils within cannot be seen, nor the filaments of they are composed.

Answered 9/28/2016

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Dr. Alan Ali answered

Specializes in Psychiatry

Muscle fibers: Largest is muscle fibers, then myofibrils then thin (actin) & thick (myocin) filaments as smallest.

Answered 12/9/2013

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Dr. David Liu answered

Specializes in Internal Medicine and Pediatrics

Long answer: "muscle fiber" is the colloquial name for muscle cell, or myocyte, which is thus the largest unit. Myocytes in turn contain myofibrils, which contain thick filaments, composed of myosin. These units are all striated, or skeletal muscle.

Answered 6/1/2015

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