A member asked:

Invasive moderately differentiated squamous cell carcinoma.. what does this mean? severe squamous dysphasia meaning also please.

2 doctors weighed in across 2 answers

SCCA: You didn't say where the tumor is located; the site is critical to know in terms of prognosis and potential treatments. In general, squamous cell tumors arise from mucosal linings, such as the oral cavity, esophagus, or vagina. They are also found in the skin and the lung, among others. Moderately well differentiated implies a tumor that is moderately aggressive and has an intermediate prognosis.

Answered 12/24/2020

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Dr. Leena Varughese answered

Specializes in Pathology

Degree of dysplasia: Squamous cell carcinomas (scc) are categorized in well-, moderately-, and poorly- differentiated tumors based on histological criteria such as keratin production, cohesion of tumor cells, and nuclear and cellular dysplasia. Severe squamous dysplasia means in the context of invading scc that there was also scc-in situ, which is basically scc just before it invaded.

Answered 11/7/2020

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