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A member asked:
Why do wilson disease patient have a low ceruloplasmin level? is it due to wilson disease itself or low production by liver?
A doctor has provided 1 answer
Minor mystery: We do know that the liver tends to underproduce ceruloplasmin in Wilson's, but this is only the case in about 2/3 of patients and it is famously unreliable as a way of screening. The exact mechanisms still haven't been sorted out.
Answered 8/9/2014
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