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A 21-year-old member asked:

What percentage of wilson's disease patients need liver transplants?

2 doctor answers3 doctors weighed in
Dr. Lance Stein
Specializes in Hepatology
A Few: Not sure, but the overall number is very small. Wilson's has variable manifestations and not all people with 2 copies of the atp7b gene mutation with develop liver or neurologic disease. Liver transplantation is the only effective option for those with wilson's who have acute liver failure or decompensated cirrhosis. Interestingly, a liver transplant cures the disease.
Dr. Ed Friedlander
Pathology 44 years experience
I wish none did: Early detection and treatment is extremely effective in preserving health. The numbers vary tremendously depending on how good local physicians are at picking up the illness in young people before it turns deadly. With restrictions on "costly unnecessary screening", the situation will probably get worse. Best wishes.

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Last updated Jun 10, 2015
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