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A 43-year-old female asked:

I take enbrel (etanercept) shots and a couple hours after i inject the shot i get a huge knot at the injection point and it itches for days is this normal?

1 doctor answer4 doctors weighed in
Dr. EVAN Leibowitz
Rheumatology 26 years experience
Yes: Injection site reactions are one of enbrel's most common side effects. These are uncomfortable, but not serious in general. These may not occur after every injection.
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Last updated Mar 26, 2013

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