A member asked:

Do wellbutrin (bupropion) and weed have an interaction?

2 doctors weighed in across 2 answers

Not really but ..: Either one taken alone can cause agitation, anxiety, nausea and other symptoms. So if you are depressed and taking wellbutrin (bupropion) weed is not something you want to add. Weed can cause cognitive impairment, mood changes like depression or even psychosis.

Answered 12/9/2013

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Dr. Alan Ali answered

Specializes in Psychiatry

Wellbutrin/Weed: Additive effect leading to psychotic symptoms due to elevation of dopamine. Would certainly not recommend that.

Answered 4/24/2013

5.3k views

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