Is there anything promising currently in clinical development in terms of an injectable enzyme for treatment of eye floaters? ocriplasmin seems to be a step in the right direction, albeit indirectly.

Floaters: Floaters are thickenings in the vitreous jelly inside the eye. Ocriplasmin does not dissolve floaters. It just causes the vitreous to release any persistent adhesions between the vitreous and retina if the adhesions are causing problems. In very rare cases, the floaters can become dense enough to block vision and may need surgical removal. As far as i know, there is not anything in development.

Enzyme for floaters.: Unfortunately, the ocriplasmin enzyme has very specific indications and really would not work for getting rid of floaters. The problem is in finding something strong enough to hydrolyze the floaters but not harm the eye. I am not aware of any research currently being done to treat floaters this way.