A member asked:

I have a diagnosed allergy to nsaids with profound supraclavicular swelling and now have the same with prednisone and cortisone injection why?

2 doctors weighed in across 2 answers
Dr. Peter Ihle answered

Specializes in Orthopedic Surgery

Allergy 2 ?: I have not heard of an allergic react 2 steroids. U may b allergic 2 1 of the other compounds present in the tablet or the injection. U give steroids 2 people who r having an allergic reaction 2 anything. Also steroids r produced in & r always present in our bodies. Sorry but that's the best that i can do.

Answered 1/8/2013

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Anti-inflammatory: All three medications are anti-inflammatories and act on the same pathway. Nsaids are simply "non-steroidal" compared to Prednisone and cortisone which are "steroidal" anti-inflammatories. You have an intolerance to the entire class.

Answered 6/30/2014

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