I've been taking zoloft (sertraline) for 12 years. it has stopped working. is there a better substitue?

There may well be: Finding that your ssri stops working after a period of time is not unusual. You can see a psychiatrist to assess your continued need for these medicines, and select another that may help you more. Also, you could add psychotherapy to your treatment. It can be a very important part of getting well. Your family doctor may have good referral sources, and www.Psychologytoday.Com does also.