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A 31-year-old member asked:

Is it safe to take domperidone during pregnancy?

2 doctor answers12 doctors weighed in
Dr. Christopher Coller
Family Medicine 13 years experience
Category C: Domperidone is rated pregnancy category c. That is, "animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks." so, if you can avoid it, i would. As always, talk with your doc about it. There may be other ways to help lactation.
Dr. Katharine Garnier
Family Medicine 33 years experience
Many medications are Category C but when the need is sufficient, you can consider using the medication. Domperidone is to help with excessive vomiting during pregnancy, if other methods aren't effective, your doctor may consider it's use. Severe dehydration and possible malnutrition from hyperemesis is also not good for your baby. You need to discuss the choice seriously with your doctor.
Nov 27, 2011
Dr. Katharine Garnier
Family Medicine 33 years experience
I have had patients, and family, with difficult pregnancies that had to use it and done fine, but it is always a balance between potential risk and benefits...good luck with your pregnancy!
Nov 27, 2011
Dr. Steven Tucker
Specializes in Gynecology
Drugs & Pregnancy: Nothing is "safe". Drinking water is fatal, if you drink too much. Pregnancy is dangerous. 2-4% of all pregnancies have birth defects, 10% preterm labor, 8% early ruptured membranes, etc with the best care. It always boils down to how bad is it. If you can't eat or drink, then meds can avoid serious problems. These are joint decisions with your doctor reviewing pros and cons. Everyone is unique.

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Last updated May 11, 2019

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