Is it safe to take domperidone during pregnancy?

Category C: Domperidone is rated pregnancy category c. That is, "animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks." so, if you can avoid it, i would. As always, talk with your doc about it. There may be other ways to help lactation.

Drugs & Pregnancy: Nothing is "safe". Drinking water is fatal, if you drink too much. Pregnancy is dangerous. 2-4% of all pregnancies have birth defects, 10% preterm labor, 8% early ruptured membranes, etc with the best care. It always boils down to how bad is it. If you can't eat or drink, then meds can avoid serious problems. These are joint decisions with your doctor reviewing pros and cons. Everyone is unique.