A member asked:

If a man have sicklecell trait will all his children carry the trait too?

6 doctors weighed in across 6 answers

50% will have trait: Assuming his partner does not have sickle cell disease or trait, the father with sickle cell trait has a 50% chance of passing on sickle trait to his offspring.

Answered 12/31/2012

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No: If a father has sickle trait he carries only one abnormal copy of the sickle cell gene. His children have a 50% chance of getting that abnormal copy and one normal copy from the mother assuming she does not have sickle cell trait or sickle cell disease (two abnormal copies).

Answered 7/31/2013

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Two possibilities: There will always be two possibilities in the offspring of a trait carrier.They can pass on the sickle trait in one of the 2 possible genes, or pass the normal gene.He could have all his kids carry trait, or none or some.You basically flip a coin every conception to see which comes up.

Answered 6/8/2016

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Dr. Amin Ashrafzadeh answered

Specializes in Ophthalmology

No! 1/2 will.: No. If the other mate has no sickle cell or trait, then 1/2 of the off springs will continue with the trait.

Answered 10/4/2016

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50% will have trait: Assuming his partner does not have sickle cell disease or trait, the father with sickle cell trait has a 50% chance of passing on sickle trait to his offspring.

Answered 12/9/2013

5.4k views

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No choice: Statistically ,half the offspring would be expected to get the trait and half not.However, every time you conceive, you flip a coin and get what you get.Every kid might get trait, every kid might be normal, or some of either.

Answered 5/23/2016

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