A 45-year-old member asked:
is sickle-cell anemia a recessive, sex-linked trait?
2 doctor answers • 3 doctors weighed in

Dr. Caren Reavesanswered
Obstetrics and Gynecology 24 years experience
Autosomal recessive: It is recessive, meaning a person has to inherit a gene for ss from each parent to be affected, but it is not sex linked.
5.6k viewsAnswered >2 years ago

Dr. Joseph Torkildsonanswered
Pediatric Hematology and Oncology 39 years experience
Yes and no: Sickle cell disease is recessive; you need to inherit a sickle gene from both parents to get the disease. It is not x-linked, however; if it were it would affect only boys. Boys and girls are equally affected by sickle cell disease.
5.6k viewsReviewed >2 years ago
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A 49-year-old member asked:
Is sickle cell anemia inherited trait or sex linked?
2 doctor answers • 2 doctors weighed in

Dr. Steven Ginsberganswered
Hematology and Oncology 37 years experience
Inherited: Sickle cell anemia is an inherited, non-sex linked genetic mutation ( actually several mutations) that leads to the formation of an abnormal hemoglobin called hemoglobin s. If someone inherits 2 sickle cell genes (1 from each parent), then sickle cell anemia is the result. If only 1 mutation is inherited, sickle cell trait is the result. The gene is passed from parent(s) to children.
4.8k viewsAnswered >2 years ago
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Last updated Dec 10, 2020
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