A member asked:

Would diagnosed depressed person + epidural steroid injection = anxiety increased 10fold + always constricted pupils?

6 doctors weighed in across 3 answers

Steroids: Steroids are powerfully effective anti-inflammatory meds, the strongest. They also have lots of side effects. In psychiatry we see frequent reactions - mania, depression, delirium or psychosis. Anxiety would also be included. The pupillary meiosis is not familiar to me, but it may be from opiates, if you are also getting pain mgmt treatment.

Answered 3/26/2013

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It should not: Anxiety can be a consequence of steroidal injections, depressive conditions, &/or the underlying pain condition that it is being treated. These conditions can result in transient pupillary dilation via adrenergic modulation. Persistent pupillary constriction is not a common cause of the conditions listed above. Opiates, which can be used for pain, can cause pupillary constriction.

Answered 3/8/2013

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Dr. Qamar Khan answered

Specializes in Pain Management

Anxiety Yes: Anxiety definitely increases with steroid medications, whether taken orally like Prednisone or like you have with epidural steroid injection. Generally this symptom will resolve, but may take up to 2-3 weeks to resolve. Consider seeing your pcp to consider options in the meantime. Regarding your pupils, I am unsure.

Answered 6/30/2014

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