A member asked:

If 5-htp causes anxiety, isn't it a little pointless to take it for depression?

5 doctors weighed in across 2 answers

Makes sense: If you consider anxiety and depression as opposite ends of a spectrun of neurotransmitter activation, it makes sense.

Answered 3/26/2013

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Dr. James Fox answered

Not so simple: Stimulating different 5ht receptors will have different effects. 5ht1a receptors will alleviate depression and anxiety. 5ht2a and c may induce anxiety. 5-htp stimulates all those receptors. Regardless, i agree that it's pointless to take 5-htp at all. It is unlikely to treat depression or anxiety any better than a sugar pill. Serotonin isn't the only answer and it's an incomplete one at that.

Answered 10/3/2016

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