HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

Does antihistamine hdroxyzine harm the liver?

A doctor has provided 1 answer

No: While Hydroxyzine is metabolized by the liver, it's use does not harm the liver. If the individual has liver damage such as hepatitis, then the Hydroxyzine may not be metabolized as it should be and side effects such as sedation may be increased.

Dr Ali and another doctor agreed

Answered 5/7/2018

5.4k views

Thank

Related Questions

A member asked:

Is there any side effects when you take antihistamines like atarax (hydroxyzine) for a longer period?

A doctor has provided 1 answer

A member asked:

Can the antihistamine hydroxyzine pam lower the seizure threshold for someone being treated for epilepsy?

2 doctors weighed in across 2 answers

A member asked:

Can hydroxyzine cause hives? I was prescribed this antihistamine for mild anxiety & noticed breakouts on arms & chest.

A doctor has provided 1 answer

A member asked:

Can antihistamines harm my kidneys?

A doctor has provided 1 answer

A member asked:

Is it safer to take Benadryl (diphenhydramine) or hydroxyzine while taking tramadol 75-100mg?

A doctor has provided 1 answer

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more

People also searched for:

For a possible diangosis of some form of acid reflux, why would an antihistamine such as Hydroxyzine HCL be Rx'ed?
I have two different antihistamines...One is hydroxyzine and the other is is diphenhydramine..Which one will cause me to gain weight?
Why can hydroxyzine be used for anxiety but not diphenhydramine? Both are antihistamines, one derived from the other, correct?
Im taking hydroxyzine 10mg daily for anxiety then I'm also taking singulair (montelukast) for sinusitis. I understand hydroxyzine has antihistamine property. Ok?
Now knowing that older antihistamines like hydroxyzine make you gain weight, how soon after I stop taking it will I start to lose the weight?

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.