A female asked:
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is it possible to have a major depression that is not treatable, no matter what is done about it?

1 doctor answer
Dr. William Holmes
33 years experience Child Psychiatry
Sometimes: There is a small percentage of people who have "refractory depression", meaning that they do not respond to treatment. This is becoming less likely due to the variety of treatments now available. If you are someone you know has struggled with long term depression that has not responded to treatment, try not to give up. Continue to see help.
Answered on May 5, 2019
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