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A 19-year-old female asked:

is normal acth plasma level enough to conclude addison's disease?

1 doctor answer1 doctor weighed in
Dr. Dan Fisher
Internal Medicine 27 years experience
In general, no.: Too difficult to answer in 400 words, but confirmation of addison's requires a sequence of testing which must be performed and collected under standard protocols. Generally low cortisol with very high acth should suggest primary adrenal insufficiency - addison's disease. Anything else will require further testing to help sort out the various causes of low cortisol.

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Last updated Jan 30, 2015
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