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A member asked:
What is the definition or description of: tissue transglutaminase iga?
3 doctors weighed in across 2 answers
98% positve - celiac: Iga antitransglutaminase antibodies are 98% sensitive for diagnosis of celiac disease. Iga antibodies as a whole are situated on the surface lining of intestines. Iga antibodies are like the guns mounted on the old fortresses to expel enemies - the first line of defense. In celiac disease by mistake this antibody is directed against tissue transglutaminase and results in symptoms of celiac.
Answered 12/15/2012
5.4k views
Celiac disease : Since 1997, tissue transglutaminase has been recognized to be the autoantigen pathophysiologically recognized by the immune system that leads to celiac disease. Testing IgA antibodies to ttg is a diagnostic marker that for diagnosing celiac disease that is pretty reliable and relatively inexpensive. There can be false pos and false neg, though.
Answered 1/12/2015
5.3k views
Related Questions
A member asked:
My 1year old, child has, normal anti transglutaminas IgA 9.4u/ml buy anti transglutaminase is, positive, 43.2u/ml what do you diagnose?
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My age 25 years and my test result of anti transglutaminase-IgA = 3.00 U/ml and anti transglutaminase-IgG =5.07 U/ml what it means? ?
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If I have an elevated transglutaminase iga, hypothyroidism, and a mother with celiac disease. Is the likelihood that I have celiac disease.?
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Ggt of 331 non drinker. Other lfts raised. Elevated iga?
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My daughter age 3y10m her weight is 8 kg and her test result of anti transglutaminase-IgA = 2.45 U/ml and anti transglutaminase-IgG =31.79 U/ml is she normal or not??
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