Are glycerin suppositories safe for heart patients?

If used properly: Glycerin irritates the bowel lining, causing it to secrete fluids that help relieve constipation. It has no direct cardiac effects. If used to the point that it causes severe diarrhea, there can be changes in your electrolytes which can cause abnormal heart rhythm changes. The insertion of a suppository in the rectum can cause vagal nerve stimulation, rarely resulting in low heart rate and BP