My wife's shouldermakes aloud, painful click if she raises her arm laterally above horizontal.?

Needs further eval.: This symptom is caused by a problem with the tendons in the shoulder called the rotator cuff. Sometimes it is just inflammation (tendinitis) but often there is a calcium deposit, bursitis, or an impingement of the bones. Her doctor can sort this out.

I agree: This does sound like the below answer. Also, have your physician evaluate the status of her labrum, or the "gristle" of the joint. Best of luck!