Do beta blockers like toprol (metoprolol) have an affect on make sex drive or potency?

Some: Small minority of patients, it does. Speak to your physician about this side affect.

Yes: Metoprolol, the ingredient in toprol-xl has been reported to cause male sexual dysfunction. If you are experiencing this, it is best to see your doctor to have it investigated rather than stopping your medication on your own. Stopping toprol-xl suddenly can cause problems. There are other medications in the same class that are less likely to cause these side effects, but they are more expensive.

Beta blocks: Beta blockers are the main anti-hypertensive that may cause irreversible male impotence, and it is also the main drug that causes depression. It should not be given at night as it may cause sleeplessness, which is the first symptom of depression if it last long enough.