Due to jaundice. my biluribin rose upto 21.1 but after now 6.82. s. creatine increased from 2.44 to 2.96. is biluribin and creatine level related?

Not really.: Your jaundice is a manifestation of having high bilirubin in your blood for whatever erason, be it hepatitis, gallbladder issues, etc.. It means that your bile flow has/had been obstructed for a while, and it backed up so it shows up in your blood. Your creatinine shows how well your kidneys are functioning, and clearing impurities from your body, like excess bilirubin. It should be < 1.5 mg/dl.

Indirectly: Serum creatinine (marker of kidney function) does not rise or fall because of bilirubin (a marker of liver function). However, kidney function can become worse due to worsening liver function. In liver disease, the bilirubin and creatinine are used to calculate a severity of disease score called "meld". Look at this website: http://www.Cpmc.Org/advanced/liver/patients/topics/meld.Html.