A member asked:

Is polymyalgia rheumatica autoimmune if ana is negative or result of old age?

A doctor has provided 1 answer
Dr. Alfred Kim answered

Specializes in Rheumatology

PMR likely autoimm: So ANA is probably the most misinterpreted test by almost everyone: it is just a screen for autoimmunity, but not all autoimmunity. And a positive ANA does not mean disease. So, pmr is ANA negative, but still may represent an autoimmune condition. What the autoimmune target is remains unclear though. True, it is exclusively seen in older (>50-60 yo) people, and this remains unclear why also.

Answered 4/2/2018

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