Don't overintepret: 1st ?: lupus is a diagnosis based on symptoms, not labs. Someone can have (+) ana, (-) dsdna, and symptoms that can be best explained by lupus, so they have lupus. Alternatively, someone else can have (+) ANA & dsdna, but no symptoms. They do not have lupus. 2nd ?: just because something is high means it's abnormal. A unproven but latest hypothesis: dsdna ab might be a result of normal immunity.
Answered 10/24/2017
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