I suffered anaphylactic shock from microdantin some 20 years ago; as a result, i now have ms. can i safely take enablex (darifenacin)?

Maybe not: Anaphylactic shock leading to multiple sclerosis 20 years later is very unusual, so assuming this to be a solid link, then you have a very unique reaction to medications, and you need to be very careful. There are a wide range of possible adverse reactions to any medication.

I'm confused: Do not really understand the described sequence, other than you are allergic to macrodantin, which does not necessarily indicate allergy to enablex (darifenacin). If you do have ms, it has no relationship to the anaphylactic shock, and may indeed be "burned out" by now. Please sit down with your doctor and discuss all of this in great detail, as this seems far more involved than can be dealt with here.