A 46-year-old member asked:
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why do i get my old ms symptoms back when i am heated up?

3 doctor answers
Dr. Virginia Simnad
27 years experience Neurology
Old MS pathways: Electric signal transmission across nerve fibers (axons) requires good insulation (myelin). While MS inflammation is followed by myelin repair, the extent of repair may vary and is never perfect. When core body temperature goes up, some of these old MS lesioned pathways are prone to "drop the signal". This is the "uhthoff phenomenon". No permanent damage is done.
Answered on Jan 12, 2015
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Dr. Zorian Trusewych
41 years experience Allergy and Immunology
Nerve transmission: This is a well known phenomenon and was used in diagnosis in the past. It is assumed to be caused by heat slowing conduction in previously damaged nerves.
Answered on Jan 10, 2015
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Dr. Gregg Friedman
A Verified Doctor commented
A US doctor answered Learn more
Gregg L. Friedman MD Psychiatrist agrees
Apr 7, 2013
Dr. Bennett Machanic
51 years experience Neurology
Insulation: Your myelin nerve coverings are partially dysfunctional due to prior inflammatory attack and heat of any kind can cause changes in intracellular potassium resulting in symptoms. This is reversable by cooling
Answered on May 23, 2014

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