Can i take propranolol & hydrochlorothiazide at the same ?

Yes: The medications work in two different ways and can be used together if recommended by your doctor.

Meh...: These meds work together to lower blood pressure. The only real downside of the combo is that if these are your only two BP meds, there's an increased risk of development of diabetes. We usually combine a diuretic with a calcium channel blocker or ace inhibitor first but your circumstances may vary.