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A member asked:
Why do some genetic syndromes that cause hypermobility include bow legs?
A doctor has provided 1 answer
Abnl collagen & bone: Hypermobility is often linked to an abnormality in the makeup of the collagen that is a significant part of the capsule/ligaments the contain a joint. The abnormal collagen often does not respond well to our routine surgicalattempts to tighten the native tissue. Likewise the ultrastructure of the bones in many genetic syndromes is also abnormal & unable to withstand the normal forces, thus bending.
Answered 12/1/2012
5.5k views
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