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Philadelphia, PA
A 63-year-old female asked:

Why do some genetic syndromes that cause hypermobility include bow legs?

1 doctor answer1 doctor weighed in
Dr. Thomas Deberardino
Orthopedic Surgery 34 years experience
Abnl collagen & bone: Hypermobility is often linked to an abnormality in the makeup of the collagen that is a significant part of the capsule/ligaments the contain a joint. The abnormal collagen often does not respond well to our routine surgicalattempts to tighten the native tissue. Likewise the ultrastructure of the bones in many genetic syndromes is also abnormal & unable to withstand the normal forces, thus bending.
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Last updated Dec 1, 2012

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