When should i talk to my grandparents about end of life decisions?

End of life: As painful or difficult it is, the discussions should start as soon as you can. Sometimes adding a neutral party (however you want to define that) is important and can ease things. Even working with a trained attorney that is familiar in these issues is most helpful. Better sooner, rather than later when cognition is affected.

65 year old plus: In clinical practice all patients 65 years old and above must have "advance directives" clarified before they present with a serious medical emergency. Pcp's offered on the first appointment or during complete physical exams.