A member asked:

Is the pancreatic cancer hereditary?

5 doctors weighed in across 4 answers

It may be hereditary: There is some evidence that pancreatic cancer may occur more in some families. Johns hopkins was doing a study on families with pancreatic cancer where by relatives were having very close followup that included ct scanning and surgery if there was suspicion of a developing cancer. I do not know if the study is still ongoing.

Answered 12/31/2014

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Dr. Herbert Hoover answered

Specializes in - Select Specialities -

It can be hereditary: Cancer of the pancreas, like many cancers, is a genetic disease in that it is caused by mutations or changes in dna. We can be born with these changes(hereditary) or, more commonly, they are acquired by chance or by exposure to chemicals or other cancer-causing agents such as found in cigarette smoke. It is currently thought that only about 10% of cases are hereditary.

Answered 12/16/2012

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Dr. Herbert Hoover answered

Specializes in - Select Specialities -

It can be hereditary: Pancreatic cancer is a genetic disease in that it is caused by mutations or changes in dna. These mutations can be inherited(hereditary) or they can develop by chance or by exposure to cancer causing chemicals or agents such as those in cigarette smoke. It is currently estimated that only approximately 10% of pancreatic cancers are hereditary.

Answered 12/16/2012

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Dr. Richard Roberts answered

Specializes in Pediatrics

It can be.: If there are two first degree relatives in a family who develop pancreatic cancer, by definition they have familial pancreatic syndrome, which is an autosomal disorder. First degree relatives are siblings, child-parent, those who are one meiosis apart. If diagnosed, you must have genetic counseling to have the risks explained. If 2 siblings are affected, each of their children has 1 in 2 risk.

Answered 6/14/2015

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